Anti-AAV8 capsid IgG2 responses were assayed in every 4 dogs
Anti-AAV8 capsid IgG2 responses were assayed in every 4 dogs. Products [BU]) at 14 days was accompanied by constant decline to full disappearance within 4-5 weeks. Subsequently, a rise in cFVIII amounts (1.5%-8%), a shortening of clotting times, and a reduction ( 90%) of bleeding episodes had been observed. Defense tolerance BMS-690514 was verified by […]