Anorgasmia (65%) and anejaculation (80%) rates in our study were higher than those in most studies of the SCI population
Anorgasmia (65%) and anejaculation (80%) rates in our study were higher than those in most studies of the SCI population. dichotomous variable. Predictors of an active and satisfactory sex life were identified using univariable and multivariable analyses. Results We evaluated 295 men with mean age of 40.7 14.5 years. Most patients had a complete SCI (65.1%) and 159 (53.9%) were incontinent. The median SHIM score was 5 (interquartile range?= 0C16) KIN-1148 and only 71 men (24.1%) had a SHIM score of at least 17. Of these men, 159 (53.9%) were sexually active. Only 63 men (39.6%) were satisfied with their sex life after SCI. In univariable analysis, all variables were associated with an active sex life. Those with a SHIM score of at least 17 had a greater likelihood of being sexually active (odds ratio?= 116, 95% confidence interval?= 14C432). EF was the only parameter associated with a satisfactory sex life (odds ratio?= 1.3, 95% confidence interval?= 1.2C1.4). Conclusions Most men with SCI were sexually inactive and/or dissatisfied with their sex life. Age, duration of SCI, completeness of SCI, continence, having a partner, and good EF were identified as predictors of an active sex life. However, only EF was a predictor of a satisfactory sex life. Gomes CM, Miranda EP, de Bessa J, et?al. Erectile Function Predicts Sexual Satisfaction in Men With Spinal Cord Injury. Sex Med 2017;5:e148Ce155. values less than .05 were considered significant and 95% CIs were used as a measure of the accuracy of the results. Analyses were performed using GraphPad Prism 5.0.3 (GraphPad Software, San Diego, CA, USA). Results Study Population A total of 295 men with a median age of 40.7 14.5 years were evaluated. The median time since SCI was 3.6 years (interquartile range [IQR]?= 1.6C7.0). The median age at time of injury was 31.3 years (IQR?= 22.7C45.4). SCI characteristics are listed in Table?1. Of these subjects, 136 (46.1%) were sexually inactive and 159 (53.9%) were sexually active. Sexual activity profiles are presented in Table?2. In our sample, 68.9% of sexually active patients were partnered, whereas 43.4% of inactive patients had a stable relationship. Of participants, 159 (53.9%) were continent and 136 (46.1%) were incontinent. For the bladder-emptying method, 201 (68.1%) performed intermittent catheterization, 83 (28.1%) KIN-1148 had spontaneous micturition, and 11 (3.8%) used an indwelling urethral catheter. Table?1 Characteristics of spinal cord injury and functional independence value .001). Only 71 men (24%) had a SHIM score of at least 17. One hundred ten men (37.2%) reported using a PDE-5 inhibitor including 58 (19.6%) who reported significant improvement of erection, 28 (9.4%) who had little improvement, and 14 (4.7%) who did not observe any benefit. Only 10 men (3.3%) reported regular use of intracavernosal injections and 3 (1%) had undergone penile implant surgery. Predictors of Sexual Activity and Satisfaction Patients’ characteristics according to sexual satisfaction status are demonstrated in Table?3. In univariable analysis, all of the following were associated with an active sex life: patient age, time since SCI, patient age at SCI, partner status, completeness of lesion, functional independence, urinary continence, and SHIM score. Of these variables, only employment status was not associated with sexual activity at univariate analysis because only SERPINB2 seven patients KIN-1148 (2.3%) were actively employed at the time of inquiry. All variables remained significant at multivariable analysis. Those with a SHIM score of?at least 17 had a greater likelihood of being sexually active (OR?= 116, 95% CI?= 14C432, 0.001) compared with men with moderate to severe ED (SHIM score 17; Table?4). Table?3 Distribution of different variables according to sexual satisfaction valuevalue .001) compared with men with moderate to severe ED (SHIM score ?17). Figure?1 illustrates the difference in SHIM scores when comparing dissatisfied with satisfied subjects. Of sexually.